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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
P36543
USC-OGP 2-DE database
:
P36543
P36543
General information about the entry
View entry in simple text format
Entry name
VATE1_HUMAN
Primary accession number
P36543
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=V-type proton ATPase subunit E 1; Short=V-ATPase subunit E 1; AltName: Full=V-ATPase 31 kDa subunit; Short=p31; AltName: Full=Vacuolar proton pump subunit E 1;.
Gene name
Name=ATP6V1E1
Synonyms=ATP6E, ATP6E2
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1252
:
pI=7.02; Mw=30801
SPOT OGP-1254
:
pI=7.14; Mw=30714
Cross-references
UniProtKB/Swiss-Prot
P36543; VATE1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
VATE1_HUMAN
Primary accession number
P36543
Secondary accession number(s)
A8MUE4 A8MUN4
Sequence was last modified on
June 1, 1994 (version 1)
Annotations were last modified on
March 15, 2017 (version 173)
Name and origin of the protein
Description
RecName: Full=V-type proton ATPase subunit E 1; Short=V-ATPase subunit E 1; AltName: Full=V-ATPase 31 kDa subunit; Short=p31; AltName: Full=Vacuolar proton pump subunit E 1;
Gene name
Name=ATP6V1E1
Synonyms=ATP6E, ATP6E2
Encoded on
Name=ATP6V1E1; Synonyms=ATP6E, ATP6E2
Keywords
Acetylation
;
Alternative splicing
;
Complete proteome
;
Direct protein sequencing
;
Hydrogen ion transport
;
Hydrolase
;
Ion transport
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Transport
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X76228; CAA53814.1
; -; mRNA
EMBL
X71491; CAA50592.1
; -; mRNA
EMBL
CR456385; CAG30271.1
; -; mRNA
EMBL
AK294623; BAG57804.1
; -; mRNA
EMBL
AK315941; BAH14312.1
; -; mRNA
EMBL
AC004019; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AC006285; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AC007666; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
BC004443; AAH04443.1
; -; mRNA
CCDS
CCDS13745.1; -. [P36543-1]
; .
CCDS
CCDS42977.1; -. [P36543-2]
; .
CCDS
CCDS42978.1; -. [P36543-3]
; .
PIR
S60562; S60562
; .
RefSeq
NP_001034455.1; NM_001039366.1. [P36543-2]
; .
RefSeq
NP_001034456.1; NM_001039367.1. [P36543-3]
; .
RefSeq
NP_001687.1; NM_001696.3. [P36543-1]
; .
UniGene
Hs.517338; -
; .
ProteinModelPortal
P36543; -
; .
SMR
P36543; -
; .
BioGrid
107012; 60
; .
IntAct
P36543; 12
; .
MINT
MINT-5002575; -
; .
STRING
9606.ENSP00000253413; -
; .
TCDB
3.A.2.2.4; the h(+)- or na(+)-translocating f-type
; v-type and a-type atpase (f-atpase) superfamily; .
iPTMnet
P36543; -
; .
PhosphoSitePlus
P36543; -
; .
SwissPalm
P36543; -
; .
BioMuta
ATP6V1E1; -
; .
DMDM
549207; -
; .
UCD-2DPAGE
P36543; -
; .
EPD
P36543; -
; .
PaxDb
P36543; -
; .
PeptideAtlas
P36543; -
; .
PRIDE
P36543; -
; .
DNASU
529; -
; .
Ensembl
ENST00000253413; ENSP00000253413
; ENSG00000131100. [P36543-1]; .
Ensembl
ENST00000399796; ENSP00000382694
; ENSG00000131100. [P36543-3]; .
Ensembl
ENST00000399798; ENSP00000382696
; ENSG00000131100. [P36543-2]; .
GeneID
529; -
; .
KEGG
hsa:529; -
; .
UCSC
uc002zms.3; human. [P36543-1]
; .
CTD
529; -
; .
DisGeNET
529; -
; .
GeneCards
ATP6V1E1; -
; .
HGNC
HGNC:857; ATP6V1E1
; .
HPA
CAB009528; -
; .
HPA
CAB018699; -
; .
HPA
HPA029196; -
; .
MIM
108746; gene
; .
neXtProt
NX_P36543; -
; .
OpenTargets
ENSG00000131100; -
; .
PharmGKB
PA25158; -
; .
eggNOG
KOG1664; Eukaryota
; .
eggNOG
COG1390; LUCA
; .
GeneTree
ENSGT00390000002730; -
; .
HOGENOM
HOG000202506; -
; .
HOVERGEN
HBG002309; -
; .
InParanoid
P36543; -
; .
KO
K02150; -
; .
OMA
EYQTVLT; -
; .
OrthoDB
EOG091G0OGO; -
; .
PhylomeDB
P36543; -
; .
TreeFam
TF313479; -
; .
BioCyc
MetaCyc:HS05489-MONOMER; -
; .
Reactome
R-HSA-1222556; ROS
; RNS production in phagocytes; .
Reactome
R-HSA-77387; Insulin receptor recycling
; .
Reactome
R-HSA-917977; Transferrin endocytosis and recycling
; .
Reactome
R-HSA-983712; Ion channel transport
; .
ChiTaRS
ATP6V1E1; human
; .
GeneWiki
ATP6V1E1; -
; .
GenomeRNAi
529; -
; .
PRO
PR:P36543; -
; .
Proteomes
UP000005640; Chromosome 22
; .
Bgee
ENSG00000131100; -
; .
CleanEx
HS_ATP6V1E1; -
; .
ExpressionAtlas
P36543; baseline and differential
; .
Genevisible
P36543; HS
; .
GO
GO:0016324; C:apical plasma membrane
; ISS:UniProtKB; .
GO
GO:0005829; C:cytosol
; ISS:UniProtKB; .
GO
GO:0005768; C:endosome
; ISS:UniProtKB; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005765; C:lysosomal membrane
; IDA:UniProtKB; .
GO
GO:0005902; C:microvillus
; IEA:Ensembl; .
GO
GO:0005739; C:mitochondrion
; IEA:Ensembl; .
GO
GO:0016469; C:proton-transporting two-sector ATPase complex
; TAS:ProtInc; .
GO
GO:0033178; C:proton-transporting two-sector ATPase complex
; catalytic domain; IEA:InterPro
GO
GO:0051117; F:ATPase binding
; IPI:UniProtKB; .
GO
GO:0008553; F:hydrogen-exporting ATPase activity
; phosphorylative mechanism; IEA:Ensembl
GO
GO:0046961; F:proton-transporting ATPase activity
; rotational mechanism; IEA:InterPro
GO
GO:0015991; P:ATP hydrolysis coupled proton transport
; IEA:Ensembl; .
GO
GO:0008286; P:insulin receptor signaling pathway
; TAS:Reactome; .
GO
GO:0034220; P:ion transmembrane transport
; TAS:Reactome; .
GO
GO:0090383; P:phagosome acidification
; TAS:Reactome; .
GO
GO:0015992; P:proton transport
; TAS:ProtInc; .
GO
GO:0016241; P:regulation of macroautophagy
; NAS:ParkinsonsUK-UCL; .
GO
GO:0033572; P:transferrin transport
; TAS:Reactome; .
HAMAP
MF_00311; ATP_synth_E_arch
; 1; .
InterPro
IPR002842; ATPase_V1/A1-cplx_esu
; .
Pfam
PF01991; vATP-synt_E
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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